%0 Journal Article %T Morphological alterations induced by the exposure to TiO2 nanoparticles in primary cortical neuron cultures and in the brain of rats %A Annica Frau %A Denis Nonclercq %A Dimitri Stanicki %A Laurence Ris %A Pascaline Rugira %A Paula Paci %A Pauline Deneufbourg %A Sophie Laurent %A Xavier Valentini %J Archive of "Toxicology Reports". %D 2018 %R 10.1016/j.toxrep.2018.08.006 %K NPs %K nanoparticles %K BBB %K blood-brain barrier %K ROS %K reactive oxygen species %K MDA %K malondialdehyde %K NO %K nitric oxide %K IL-1¦Â %K interleukin-1¦Â %K TNF-¦Á %K tumor necrosis factor-¦Á %K IL-10 %K interleukin-10 %K IP %K intraperitoneal %K DLS %K dynamic light scattering %K HBSS %K Hank's balanced salt solution %K FBS %K fetal bovine serum %K BrdU %K 5-Bromo-2¡ä-deoxyuridine %K SEM %K standard error of the mean %K MAP2 %K microtubule-associated protein 2 %K GFAP %K glial fibrillary acidic protein %K 4-HNE %K 4-hydroxynonenal %K NMDA %K N-methyl-D-aspartate %K NOS %K nitric oxide synthase %K ATP %K adenosine triphosphate %K CNS %K central nervous system Nanoparticles %K Brain %K Cell culture %K Oxidative stress %K Proliferation %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118103/