%0 Journal Article %T Choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial ¨C the development of the DELTA2 guidance %A Catherine Hewitt %A Craig Robert Ramsay %A Dean A. Fergusson %A Doug Altman %A Jesse A. Berlin %A Joanne C. Rothwell %A Jonathan Alistair Cook %A Lisa V. Hampson %A Luke David Vale %A Martin Bland %A Richard Emsley %A Stephen J. Walters %A Steven A. Julious %A William Sones %J Archive of "Trials". %D 2018 %R 10.1186/s13063-018-2887-x %K Target difference %K Clinically important difference %K Sample size %K Guidance %K Randomised trial %K Effect size %K Delphi %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180499/