%0 Journal Article
%T Chemical constituents of tobacco smoke induce the production of interleukin-8 in human bronchial epithelium, 16HBE cells
%A Chengyun Xu
%A Chunyun Shi
%A Fangfang Huang
%A Guojun Zhou
%A Weiqiang Xiao
%A Xiaokai Wu
%A Ximei Wu
%A Xinbo Lu
%A Yajun Hu
%J Archive of "Tobacco Induced Diseases".
%D 2016
%R 10.1186/s12971-016-0089-4
%X Interleukin-8 (IL-8) functions as a major chemoattractant and plays pivotal roles in the initiation and development of chronic obstructive pulmonary disease (COPD), and tobacco smoke is a most risk factor contributing to the development of COPD. Hence, we have screened some of the tobacco smoke-derived chemical compounds that potentially induce the production of IL-8 in human bronchial epithelium, 16HBE cells
%K Interleukin-8
%K Tobacco smoke
%K Human bronchial epithelium
%K Nicotine
%K Benzopyrene
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950078/