%0 Journal Article
%T Derivation and validation of a two-biomarker panel for diagnosis of ARDS in patients with severe traumatic injuries
%A Addison K May
%A Carolyn S Calfee
%A David R Janz
%A Lorraine B Ware
%A Matthew W Semler
%A Michael A Matthay
%A Mitchell J Cohen
%A Richard D Fremont
%A Ryan M Brown
%A Tatsuki Koyama
%A Zhiguo Zhao
%J Archive of "Trauma Surgery & Acute Care Open".
%D 2017
%R 10.1136/tsaco-2017-000121
%X Acute respiratory distress syndrome (ARDS) is common after severe traumatic injuries but is underdiagnosed and undertreated. We hypothesized that a panel of plasma biomarkers could be used to diagnose ARDS in severe trauma. To test this hypothesis, we derived and validated a biomarker panel in three independent cohorts and compared the diagnostic performance to clinician recognition of ARDS
%K acute lung injury
%K ARDS
%K endothelium
%K lung epithelium
%K trauma
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887582/