%0 Journal Article
%T Reproducible grey matter patterns index a multivariate, global alteration of brain structure in schizophrenia and bipolar disorder
%A Alessandro Bertolino
%A Alex J Ing
%A Andreas Meyer-Lindenberg
%A Andreas Papassotiropoulos
%A Andrew M McIntosh
%A Barbara Franke
%A Dirk J Heslenfeld
%A Dominique J-F de Quervain
%A Emanuel Schwarz
%A Giulio Pergola
%A Giuseppe Blasi
%A Gunter Schumann
%A Heike Tost
%A Ingrid Agartz
%A Jan K Buitelaar
%A Jeremy Hall
%A Lars T Westlye
%A Lena Flyckt
%A Marcella Bellani
%A Marcella Rietschel
%A Markus M N£¿then
%A Mathias Zink
%A Nhat Trung Doan
%A Ole A Andreassen
%A Paolo Brambilla
%A Pasquale Di Carlo
%A Peter Kirsch
%A Quentin Noirhomme
%A Ralph Brecheisen
%A Robbert L Harms
%A Simon Cervenka
%A Sophia Frangou
%A Stephanie H Witt
%A The IMAGEMEND Consortium
%A Karolinska Schizophrenia Project (KaSP) Consortium
%A Thomas Wolfers
%A Tiril P Gurholt
%A Tiziana Quarto
%A Tobias Kaufmann
%A Torgeir Moberget
%J Archive of "Translational Psychiatry".
%D 2019
%R 10.1038/s41398-018-0225-4
%X Normalization models were built in training data only and these models were subsequently applied to adjust the test data. The same normalization strategy was applied for global structural parameters, which were subsequently used to remove the global structural signal from VBM- / FreeSurfer-based features. The resulting data was used for leave-site-out cross-validation analyses. For univariate analyses, as well as for machine learning analyses performed on the entire dataset, data were additionally corrected for a site factor, to account for the impact of site differences (see methods
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341112/