%0 Journal Article
%T Neonatal Alloimmune Neutropenia
%A Leendert Porcelijn
%A Masja de Haas
%J Archive of "Transfusion Medicine and Hemotherapy".
%D 2018
%R 10.1159/000492949
%X Neonatal alloimmune neutropenia (NAIN, NAIN or NIN) is a neutrophil blood group antagonism, analogous to hemolytic disease of the fetus and newborn (HDFN) and fetal/neonatal alloimmune thrombocytopenia (FNAIT). A limited number of prospective screening studies showed that granulocyte-specific antibodies were detectable in 0.35-1.1% of random postnatal maternal samples and that the incidence of NAIN was below 0.1%. Symptoms vary from none to mild skin infections, omphalitis or more severe infections like pneumonia, sepsis, and meningitis. Treatment of neonatal infection with antibiotics and granulocyte-colony stimulating factor is advised
%K Fetal alloimmune thrombocytopenia
%K Hemolytic disease of the newborn
%K Neonatal alloimmune neutropenia
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489100/