%0 Journal Article %T Diagnostic Investigations of Gastroesophageal Reflux Disease: Who and When to Refer and for What Test? %A Arne Kandulski %A Lukas Moleda %A Martina M¨šller-Schilling %J Archive of "Visceral Medicine". %D 2018 %R 10.1159/000488184 %X Due to the high prevalence and incidence of patients with gastroesophageal reflux disease (GERD), the diagnostic workup of patients with symptoms of GERD needs to be balanced between empiric antisecretory therapy and further functional assessment including endoscopy and reflux monitoring %K Gastroesophageal reflux disease %K pH-metry %K Diagnostics %K Therapy %K Proton pump inhibitors %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981635/