%0 Journal Article %T p-Benzoquinone initiates non-invasive urothelial cancer through aberrant tyrosine phosphorylation of EGFR, MAP kinase activation and cell cycle deregulation: Prevention by vitamin C %A Ayan Chandra %A Dhruba J. Chattopadhyay %A Indu B. Chatterjee %A Shinjini Ganguly %J Archive of "Toxicology Reports". %D 2017 %R 10.1016/j.toxrep.2017.06.005 %K Bax %K BCL2-associated X protein %K Bcl-2 %K B-cell lymphoma 2 %K CS %K cigarette smoke %K DNPH %K 2 4-dinitrophenylhydrazine %K GAPDH %K glyceraldehyde 3-phosphate dehydrogenase %K IARC %K International Agency for Research on Cancer %K p-BQ %K p-benzoquinone %K p-BSQ %K p-benzosemiquinone %K PAHs %K polycyclic aromatic hydrocarbons %K PBS %K phosphate buffered saline %K ROS %K reactive oxygen species %K SDS PAGE %K sodium dodecyl sulfate polyacrylamide gel electrophoresis %K TUNEL %K terminal deoxynucleotidyl transferase dUTP nick end labelling %K WHO %K World Health Organization %K UC %K urothelial carcinoma %K CIS %K carcinoma in situ %K EGFR %K epidermal growth factor receptor %K MAPK %K mitogen activated protein kinase p-Benzoquinone %K Carcinoma in situ %K Dysplasia %K Aberrant EGFR activation %K Cell cycle deregulation %K Vitamin C %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615141/