%0 Journal Article
%T Traditional clinical criteria outperform high-sensitivity C-reactive protein for the screening of hepatic nuclear factor 1 alpha maturity-onset diabetes of the young among young Asians with diabetes
%A Daphne Su-Lyn Gardner
%A Jaydutt Bhalshankar
%A Katharine R. Owen
%A Rashida Farhad Vasanwala
%A Suresh Rama Chandran
%A Yi Zhao
%J Archive of "Therapeutic Advances in Endocrinology and Metabolism".
%D 2018
%R 10.1177/2042018818776167
%X Young adults with diabetes in Asia represent a heterogeneous group. Using traditional clinical criteria to preselect individuals for testing for maturity-onset diabetes of the young (MODY) may exclude a large proportion from testing. High-sensitivity C-reactive protein (hs-CRP) has shown promise as a biomarker to differentiate hepatic nuclear factor 1 alpha (HNF1A)-MODY from type 2 diabetes. We aimed to compare the use of hs-CRP as a biomarker versus traditional criteria, to guide testing for HNF1A-MODY among a cohort of young adults with diabetes in Singapore
%K hs-CRP
%K HNF1A-MODY
%K MODY
%K monogenic diabetes
%K young-onset diabetes
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116767/