%0 Journal Article %T Lung Volume Reduction in Advanced Emphysema %A Nicholas S Hopkinson %J Archive of "Tanaffos". %D 2017 %X Hyperinflation is a cardinal feature of COPD associated with reduced daily physical activity and increased mortality. Although bronchodilators and pulmonary rehabilitation have some effect many patients with COPD remain highly symptomatic %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684712/