%0 Journal Article %T Acute Respiratory Failure as the First Manifestation of Antisynthetase Syndrome %A Abir Hedhli %A Amani Ben Mansour %A Jouda Cherif %A Majed Beji %A Meriem Mjid %A Sonia Toujani %A Yassine Ouahchy %J Archive of "Tanaffos". %D 2017 %X We report the case of a 40-year-old man with acute respiratory failure syndrome that later proved to be an initial manifestation of antisynthetase syndrome. The diagnosis of this rare combination of a connective tissue disease and an acute respiratory failure is difficult in a previously asymptomatic patient. Early diagnosis and immunosuppressive therapy started precociously prevented the disease progression and resulted in a good outcome %K Antisynthetase syndrome %K Respiratory failure %K Interstitial lung disease %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473386/