%0 Journal Article
%T Inflammation and atherosclerosis: fulfilling Koch¡¯s postulates
%A Ishwarlal Jialal
%A Naval K. Vikram
%J Archive of "Therapeutic Advances in Cardiovascular Disease".
%D 2018
%R 10.1177/1753944717744740
%X Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of mortality in the Western world. Atherogenesis is an inflammatory process originating from a nascent fatty streak lesion culminating in plaque rupture.1¨C4 Various biomediators of inflammation, including adhesion molecules, cytokines, chemokines, etc., are known to play a role in atherosclerosis in both animal models and humans. The prototypic marker of inflammation, high-sensitivity C-reactive protein (hsCRP) for example, has previously been shown to independently predict cardiovascular events (CVE).1¨C
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933640/