%0 Journal Article
%T Colon Cancer Cell Secretes EGF to Promote M2 Polarization of TAM Through EGFR/PI3K/AKT/mTOR Pathway
%A Fujun Li
%A Guanghui Lian
%A Junwen Yang
%A Linlin Chen
%A Miao Ouyang
%A Shuijiao Chen
%J Archive of "Technology in Cancer Research & Treatment".
%D 2019
%R 10.1177/1533033819849068
%X Tumor environment has been recognized to affect cancer cell progression, such as tumor-associated macrophages. However, increasing evidences suggest that tumor cells are capable of regulating polarization of tumor-associated macrophages. In this study, we investigate the mechanism of how colon cancer cell impacts tumor-associated macrophages polarization
%K macrophage
%K M2 polarization
%K colon cancer cell
%K EGF/EGFR
%K PI3K/AKT/mTOR pathway
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535704/