%0 Journal Article
%T Time course of lymphocyte repopulation after dimethyl
fumarate-induced grade 3 lymphopenia: contribution of patient
age
%A Andrei Miclea
%A Andrew Chan
%A Anke Salmen
%A Christoph Friedli
%A Lara Diem
%A Maud Bagnoud
%A Myriam Briner
%A Robert Hoepner
%J Archive of "Therapeutic Advances in Neurological Disorders".
%D 2019
%R 10.1177/1756286419843450
%X Dimethyl fumarate (DMF) is licensed for treatment of relapsing¨Cremitting multiple sclerosis (RRMS). DMF can induce lymphopenia, which is assumed to increase the risk for opportunistic infections like progressive multifocal leukoencephalopathy. Our goal for this work was to estimate the frequency of grade 3 lymphopenia in DMF-treated patients with RRMS and to characterize patient-sided factors influencing the time course of lymphocyte repopulation after DMF withdrawal
%K adverse event
%K age
%K fumarate
%K multiple sclerosis
%K lymphocytes
%K white blood cells
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506915/