%0 Journal Article %T Radiomics: a novel feature extraction method for brain neuron degeneration disease using 18F-FDG PET imaging and its implementation for Alzheimer¡¯s disease and mild cognitive impairment %A Chuantao Zuo %A Huiwei Zhang %A Jiaying Lu %A Jiehui Jiang %A Juanjuan Jiang %A Yupeng Li %J Archive of "Therapeutic Advances in Neurological Disorders". %D 2019 %R 10.1177/1756286419838682 %X Alzheimer¡¯s disease (AD) is the most common form of progressive and irreversible dementia, and accurate diagnosis of AD at its prodromal stage is clinically important. Currently, computer-aided diagnosis of AD and mild cognitive impairment (MCI) using 18F-fluorodeoxy-glucose positron emission tomography (18F-FDG PET) imaging is usually based on low-level imaging features or deep learning methods, which have difficulties in achieving sufficient classification accuracy or lack clinical significance. This research therefore aimed to implement a new feature extraction method known as radiomics, to improve the classification accuracy and discover high-order features that can reveal pathological information %K 18F-FDG PET %K Alzheimer¡¯s disease %K mild cognitive impairment %K radiomics %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444412/