%0 Journal Article %T Bisphosphonates and cardiovascular risk in elderly patients with previous cardiovascular disease: a population-based nested case-control study in Italy %A Alessandro Mugelli %A Chiara Sorge %A Cristiana Vitale %A Ersilia Lucenteforte %A Francesco Lapi %A Giovanni Corrao %A Giuseppe Roberto %A Graziano Onder %A Janet Sultana %A Marina Davoli %A Nera Agabiti %A Silvia Cascini %A Ursula Kirchmayer %J Archive of "Therapeutic Advances in Drug Safety". %D 2019 %R 10.1177/2042098619838138 %X In a globally aging population, chronic conditions with a high impact on healthcare costs and quality of life, such as osteoporosis and associated fractures, are a matter of concern. For osteoporosis, several drug treatments are available, but evidence on adverse cardiovascular and cerebrovascular (CCV) events, and in particular the risk of atrial fibrillation (AF), related to anti-osteoporotic drug use is inconclusive. The objective of this study was to evaluate the association between the use of bisphosphonates (BPs), strontium ranelate (SR), and other anti-osteoporosis drugs and the risk of AF and CCV events in a large cohort of patients affected by CCV diseases %K adverse events %K atrial fibrillation %K bisphosphonates %K cardiovascular risk %K nested case-control study %K pharmacoepidemiology %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452576/