%0 Journal Article %T A Hypoxic Environment Attenuates Exercise-Induced Procoagulant Changes Due to Decreased Platelet Activation %A Bas de Laat %A C¨¦cile H. Kicken %A Dana Huskens %A Evi Schoenmaker %A Jasper A. Remijn %A Lisa N. van der Vorm %A Suzanne Zwaveling %J Archive of "TH Open: Companion Journal to Thrombosis and Haemostasis". %D 2019 %R 10.1055/s-0039-1692991 %X Introduction £¿Although physical exercise is protective against cardiovascular disease, it can also provoke sudden cardiac death (exercise paradox). Epidemiological studies suggest that systemic hypoxia at high altitude is a risk factor for venous thromboembolism. Forthcoming, this study investigated the effect of repeated exercise at high altitude on blood coagulation, platelet function, and fibrinolysis %K exercise %K hypoxia %K thrombosis %K thrombin generation %K platelet activation %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645913/