%0 Journal Article %T Clinical effectiveness and toxicity of second-line irinotecan in advanced gastric and gastroesophageal junction adenocarcinoma: a single-center observational study %A Agnieszka Julia Slowik %A Andrzej Budzy¨½ski %A Kamil Fijorek %A Kamil Konopka %A Micha£¿ P£¿dziwiatr %A Miros£¿awa Puskulluoglu %A Sebastian Ochenduszko %J Archive of "Therapeutic Advances in Medical Oncology". %D 2017 %R 10.1177/1758834016689029 %X Randomized clinical trials showed improved overall survival (OS) of advanced gastroesophageal adenocarcinoma (GEA) patients treated with second-line taxane or irinotecan. However, most data on irinotecan efficacy in this setting come from large Asian trials. We retrospectively analyzed clinical effectiveness and toxicity of irinotecan in a cohort of patients with advanced GEA treated in our department %K gastric cancer %K gastroesophageal cancer %K irinotecan %K second-line chemotherapy %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405997/