%0 Journal Article
%T BarrettĄ¯s esophagus: novel strategies for screening and surveillance
%A Prashanthi N. Thota
%A Vedha Sanghi
%J Archive of "Therapeutic Advances in Chronic Disease".
%D 2019
%R 10.1177/2040622319837851
%X BarrettĄ¯s esophagus is the precursor lesion for esophageal adenocarcinoma. Screening and surveillance of BarrettĄ¯s esophagus are undertaken with the goal of earlier detection and lowering the mortality from esophageal adenocarcinoma. The widely used technique is standard esophagogastroduodenoscopy with biopsies per the Seattle protocol for screening and surveillance of BarrettĄ¯s esophagus. Surveillance intervals vary depending on the degree of dysplasia with endoscopic eradication therapy confined to patients with BarrettĄ¯s esophagus and confirmed dysplasia. In this review, we present various novel techniques for screening of BarrettĄ¯s esophagus such as unsedated transnasal endoscopy, cytosponge with trefoil factor-3, balloon cytology, esophageal capsule endoscopy, liquid biopsy, electronic nose, and oral microbiome. In addition, advanced imaging techniques such as narrow band imaging, dye-based chromoendoscopy, confocal laser endomicroscopy, volumetric laser endomicroscopy, and wide-area transepithelial sampling with computer-assisted three-dimensional analysis developed for better detection of dysplasia are also reviewed
%K BarrettĄ¯s esophagus
%K cytosponge
%K dysplasia
%K esophageal adenocarcinoma
%K gastroesophageal reflux disease
%K screening
%K surveillance
%K trefoil factor
%K unsedated transnasal endoscopy
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435879/