%0 Journal Article %T Letter to the Editor regarding the article ¡®Left atrial volume index in patients with heart failure and severely impaired left ventricular systolic function: the role of established echocardiographic parameters, circulating cystatin C and galectin-3¡¯ by Zivlas et al. (2017) %A Claudia Josa-Laorden %A Jorge Rubio-Gracia %A Juan P¨¦rez-Calvo %J Archive of "Therapeutic Advances in Cardiovascular Disease". %D 2018 %R 10.1177/1753944718756545 %X We have read the article by Zivlas and colleagues in which the authors suggest a putative pathogenic role for cystatin C (Cys-C) and galectin-3 (Gal-3) in heart failure (HF) progression and cardiorenal syndrome. They even speculate on the possibility of targeting both molecules as a new therapeutic approach to address both processes. %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956948/