%0 Journal Article
%T Autoimmune encephalitis associated with antibodies against the metabotropic glutamate receptor type 1: case report and review of the literature
%A Antonios Bayas
%A Corinna Bien
%A Markus Naumann
%A Monika Christ
%A Thomas Hagen
%A Torsten M¨¹ller
%J Archive of "Therapeutic Advances in Neurological Disorders".
%D 2019
%R 10.1177/1756286419847418
%X Autoimmune encephalitis associated with antibodies against the metabotropic glutamate receptor type 1 is a rare autoimmune disease with only 18 cases being described in the literature so far. Most patients present with subacute cerebellar ataxia. In more than one third of cases a paraneoplastic aetiology has been suspected. Here we report a case of a 45-year-old man without known malignancy, who presented with progressive dysarthria and subsequently developed subacute cerebellar ataxia. Immunotherapy with glucocorticoids, i.v. immunoglobulins and rituximab improved clinical symptoms and resulted in a stable disease course up to the present. The article describes the clinical course of the patient with a follow-up-period of approximately 24£¿months and reviews the cases reported in the literature so far
%K ataxia
%K autoimmune encephalitis
%K dysarthria
%K metabotropic glutamate receptor type 1
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535747/