%0 Journal Article
%T The endonuclease APE1 processes miR-92b formation, thereby regulating
expression of the tumor suppressor LDLR in cervical cancer cells
%A Guiqian Zhang
%A Ya Xu
%A Yi Sun
%A Yun Feng
%J Archive of "Therapeutic Advances in Medical Oncology".
%D 2019
%R 10.1177/1758835919855859
%X The molecular mechanisms underlying cervical cancer require elucidation to identify novel therapeutic targets. Apurinic/apyrimidinic endodeoxyribonuclease 1 (APE1) is a multifunctional apurinic/apyrimidinic (AP) endonuclease that influences the transcription of many cancer-related genes via microRNome regulation. Herein, we examine the role of miR-92b-3p (hereinafter miR-92b), whose processing may be regulated by APE1, in cervical cancer progression
%K APE1
%K cervical cancer
%K LDLR
%K microRNA
%K miR-92b
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624912/