%0 Journal Article
%T Transcription of Leishmania major U2 small nuclear RNA gene is directed by extragenic sequences located within a tRNA-like and a tRNA-Ala gene
%A Elisa Figueroa-Angulo
%A Luis E. Florencio-Mart¨ªnez
%A Rebeca G. Manning-Cela
%A Rodrigo Moreno-Campos
%A Santiago Mart¨ªnez-Calvillo
%A Sa¨²l Rojas-S¨¢nchez
%J Archive of "Parasites & Vectors".
%D 2016
%R 10.1186/s13071-016-1682-3
%X Leishmania and other trypanosomatid parasites possess atypical mechanisms of gene expression, including the maturation of mRNAs by trans-splicing and the involvement of RNA Polymerase III in transcription of all snRNA molecules. Since snRNAs are essential for trans-splicing, we are interested in the study of the sequences that direct their expression. Here we report the characterization of L. major U2 snRNA promoter region
%K Leishmania
%K U2 snRNA
%K Promoter region
%K tRNA-like
%K Pseudouridine
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950102/