%0 Journal Article
%T Twenty-six circulating antigens and two novel diagnostic candidate molecules identified in the serum of canines with experimental acute toxoplasmosis
%A Huajing Zhang
%A Junxin Xue
%A Kehe Huang
%A Quan Wang
%A Wei Jiang
%A Yan Xiao
%A Yingchun Liu
%A Yongjun Chen
%A Yuanbiao Qiao
%J Archive of "Parasites & Vectors".
%D 2016
%R 10.1186/s13071-016-1643-x
%X The protozoan Toxoplasma gondii is a pathogen that causes severe opportunistic disease in a wide range of hosts. Efficient methods to diagnose acute T. gondii infection are essential for the administration of appropriate treatments and to reduce economic losses. In animals with acute infections, circulating antigens (CAgs) were detected as early as two days post-infection; these CAgs were reliable diagnostic indicators of acute infection. However, only a limited number of CAgs have been identified to date. The objective of this study was to identify a broader spectrum of CAgs and to explore novel diagnostic candidates in serum
%K Toxoplasma gondii
%K Acute infection
%K Proteomics
%K Circulating antigens
%K Diagnostic candidates
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928332/