%0 Journal Article
%T Anopheles bionomics, insecticide resistance mechanisms, and malaria transmission in the Korhogo area, northern Cˋte d＊Ivoire: a pre-intervention study
%A Alphonsine A. Koffi
%A Amal Dahounto
%A Anthony Som谷
%A Baba Coulibaly
%A Barnabas Zogo
%A Bertin N＊Cho Tchiekoi
%A C谷dric Pennetier
%A Dieudonn谷 Diloma Soma
%A Florence Fournet
%A Lamine Baba-Moussa
%A Ludovic P. Ahoua Alou
%A Nicolas Moiroux
%A Roch Kounbobr Dabir谷
%A Souleymane Kand谷
%J Archive of "Parasite".
%D 2019
%R 10.1051/parasite/2019040
%X A better understanding of malaria transmission at a local scale is essential for developing and implementing effective control strategies. In the framework of a randomized controlled trial (RCT), we aimed to provide an updated description of malaria transmission in the Korhogo area, northern Cˋte d＊Ivoire, and to obtain baseline data for the trial. We performed human landing collections (HLCs) in 26 villages in the Korhogo area during the rainy season (September每October 2016, April每May 2017) and the dry season (November每December 2016, February每March 2017). We used PCR techniques to ascertain the species of the Anopheles gambiae complex, Plasmodium falciparum sporozoite infection, and insecticide resistance mechanisms in a subset of Anopheles vectors. Anopheles gambiae s.l. was the predominant malaria vector in the Korhogo area. Overall, more vectors were collected outdoors than indoors (p < 0.001). Of the 774 An. gambiae s.l. tested in the laboratory, 89.65% were An. gambiae s.s. and 10.35% were An. coluzzii. The frequencies of the kdr allele were very high in An. gambiae s.s. but the ace-1 allele was found at moderate frequencies. An unprotected individual living in the Korhogo area received an average of 9.04, 0.63, 0.06 and 0.12 infected bites per night in September每October, November每December, February每March, and April每May, respectively. These results demonstrate that the intensity of malaria transmission is extremely high in the Korhogo area, especially during the rainy season. Malaria control in highly endemic areas such as Korhogo needs to be strengthened with complementary tools in order to reduce the burden of the disease
%K Malaria
%K Vectors
%K Resistance
%K Intensity of transmission
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625791/