%0 Journal Article
%T Successful use of ofatumumab in two cases of early-onset juvenile SLE with thrombocytopenia caused by a mutation in protein kinase C ¦Ä
%A Despina Eleftheriou
%A Iek Leng Cheng
%A Linda Lei
%A Muthana Al-Obaidi
%A Neil Sebire
%A Paul Brogan
%A Sabina Muhammad
%J Archive of "Pediatric Rheumatology Online Journal".
%D 2018
%R 10.1186/s12969-018-0278-1
%X Pedigree of the family and renal histology. a The affected siblings (shaded) are homozygous for the PRKCD mutation as indicated and the parents are carriers of the mutation. WT, wild type. b Low power (Periodic acid¨CSchiff stain, original magnification ¡Á£¿40) and Fig. 1c higher power (Haematoxylin and Eosin stain, original magnification ¡Á£¿200) showing severe acute tubulointerstitial nephritis with marked predominantly mononuclear inflammatory infiltrate and associated mild acute tubular damag
%K Ofatumumab
%K Juvenile SLE
%K Rituximab
%K Protein kinase C ¦Ä deficiency
%K Acute tubulointerstitial nephritis
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158832/