%0 Journal Article
%T Dextran sulfate inhibits acute Toxoplama gondii infection in pigs
%A Akiko Ishiwa
%A Atsuko Inomata
%A Fumikazu Matsuhisa
%A Kenji Koyama
%A Kentaro Kato
%A Mohamad Alaa Terkawi
%A Noriyuki Horiuchi
%A Shinya Fukumoto
%A Yohsuke Ogawa
%A Yuho Murata
%J Archive of "Parasites & Vectors".
%D 2016
%R 10.1186/s13071-016-1421-9
%X Toxoplasma gondii is a highly prevalent protozoan that can infect all warm-blooded animals, including humans. Its definitive hosts are Felidae and its intermediate hosts include various other mammals and birds, including pigs. It is found in the meat of livestock which is a major source of human infection. Hence the control of toxoplasmosis in pigs is important for public health. We previously showed that dextran sulfate (DS), especially DS10 (dextran sulfate MW 10 kDa), is effective against T. gondii infection both in vitro and in mice. In this study, we asked whether DS affects T. gondii infection of pigs, one of the main animal sources of toxoplasmosis transmission to humans
%K Dextran sulfate
%K Intermediate host
%K Pig
%K Public health
%K Toxoplasma gondii
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784389/