%0 Journal Article
%T Oxidative stress and the presence of bacteria increase gene expression of the antimicrobial peptide aclasin, a fungal CS¦Á¦Â defensin in Aspergillus clavatus
%A Gabriela Contreras
%A Holger Sch£¿fer
%A Michael Wink
%A Nessa Wang
%J Archive of "PeerJ".
%D 2019
%R 10.7717/peerj.6290
%X Antimicrobial peptides (AMPs) represent a broad class of naturally occurring antimicrobial compounds. Plants, invertebrates and fungi produce various AMPs as, for example, defensins. Most of these defensins are characterised by the presence of a cysteine-stabilised ¦Á-helical and ¦Â-sheet (CS¦Á¦Â) motif. The changes in gene expression of a fungal CS¦Á¦Â defensin by stress conditions were investigated in Aspergillus clavatus. A. clavatus produces the CS¦Á¦Â defensin Aclasin, which is encoded by the aclasin gene
%K Antimicrobial peptides
%K Defensins
%K Gene expression
%K Oxidative stress
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394349/