%0 Journal Article
%T Insight into the maintenance of odontogenic potential in mouse dental mesenchymal cells based on transcriptomic analysis
%A Dandan Yang
%A Duanqing Pei
%A Jinglei Cai
%A Lihong Ge
%A Lingfei Jia
%A Pengfei Liu
%A Shicheng Wei
%A Shubin Chen
%A Waner Hu
%A Yuming Zhao
%A Yunfei Zheng
%J Archive of "PeerJ".
%D 2016
%R 10.7717/peerj.1684
%X Background. Mouse dental mesenchymal cells (mDMCs) from tooth germs of cap or later stages are frequently used in the context of developmental biology or whole-tooth regeneration due to their odontogenic potential. In vitro-expanded mDMCs serve as an alternative cell source considering the difficulty in obtaining primary mDMCs; however, cultured mDMCs fail to support tooth development as a result of functional failures of specific genes or pathways. The goal of this study was to identify the genes that maintain the odontogenic potential of mDMCs in culture
%K Odontogenesis
%K Odontogenic potential
%K RNA-Seq
%K Transcriptome
%K Mouse dental mesenchymal cells
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768683/