%0 Journal Article
%T Exploring the transcriptome of luxI£¿ and ¦¤ainS mutants and the impact of N-3-oxo-hexanoyl-L- and N-3-hydroxy-decanoyl-L-homoserine lactones on biofilm formation in Aliivibrio salmonicida
%A Erik Hjerde
%A Hilde Hansen
%A Jostein A. Johansen
%A Miriam Khider
%A Nils Peder Willassen
%J Archive of "PeerJ".
%D 2019
%R 10.7717/peerj.6845
%X Bacterial communication through quorum sensing (QS) systems has been reported to be important in coordinating several traits such as biofilm formation. In Aliivibrio salmonicida two QS systems the LuxI/R and AinS/R, have been shown to be responsible for the production of eight acyl-homoserine lactones (AHLs) in a cell density dependent manner. We have previously demonstrated that inactivation of LitR, the master regulator of the QS system resulted in biofilm formation, similar to the biofilm formed by the AHL deficient mutant ¦¤ainSluxI£¿. In this study, we aimed to investigate the global gene expression patterns of luxI and ainS autoinducer synthases mutants using transcriptomic profiling. In addition, we examined the influence of the different AHLs on biofilm formation
%K Quorum sensing
%K Acyl homoserine lactone
%K Aliivibrio salmonicida
%K Biofilm
%K Exopolysccharides
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499059/