%0 Journal Article
%T Biological Effects of Hesperetin on Interleukin-6/Phosphorylated Signal Transducer and Activator of Transcription 3 Pathway Signaling in Prostate Cancer PC3 Cells
%A Esfandiar Heidarian
%A Moein Shirzad
%A Mostafa Gholami-Arjenaki
%A Pezhman Beshkar
%J Archive of "Pharmacognosy Research".
%D 2017
%R 10.4103/0974-8490.204655
%X Interleukin-6 (IL-6) is a multifunctional glycoprotein that regulates the growth of some tumors, including prostate carcinomas due to signal transducer and activator of transcription 3 (STAT3), extracellular signal-regulated kinases 1/2 (ERK1/2), and AKT signaling pathways. Hesperetin, as a flavanone, has several biological properties such as antitumor and anti-inflammatory
%K Hesperetin
%K interleukin-6
%K pAKT
%K phosphorylated extracellular signal-regulated kinases 1/2
%K phosphorylated signal transducer and activator of transcription 3
%K prostate cancer
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424561/