%0 Journal Article
%T Variable and Variant Protein Multigene Families in Babesia bovis Persistence
%A David R. Allred
%J Archive of "Pathogens".
%D 2019
%R 10.3390/pathogens8020076
%X Cattle infected with Babesia bovis face a bifurcated fate: Either die of the severe acute infection, or survive and carry for many years a highly persistent but generally asymptomatic infection. In this review, the author describes known and potential contributions of three variable or highly variant multigene-encoded families of proteins to persistence in the bovine host, and the mechanisms by which variability arises among these families. Ramifications arising from this variability are discussed
%K Babesia
%K persistent infection
%K antigenic variation
%K cytoadhesion
%K immunodominance
%K immune evasion
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630957/