%0 Journal Article %T Associations among the plasma amino acid profile, obesity, and glucose metabolism in Japanese adults with normal glucose tolerance %A Asuka Yamada %A Chisa Takashina %A Daisuke Ikeda %A Hiroshi Ohira %A Ichizo Tsujino %A Masaharu Nishimura %A Noriko Oyama-Manabe %A Shinji Sakaue %A Takahiro Sato %A Taku Watanabe %A Yoichi M. Ito %A Yoshinori Otsuka %J Archive of "Nutrition & Metabolism". %D 2016 %R 10.1186/s12986-015-0059-5 %X Amino acids (AAs) are emerging as a new class of effective molecules in the etiology of obesity and diabetes mellitus. However, most investigations have focused on subjects with obesity and/or impaired glucose regulation; the possible involvement of AAs in the initial phase of glucose dysregulation remains poorly understood. Furthermore, little attention has been given to possible associations between the pattern/degree of fat deposition and the plasma AA profile. Our objective was therefore to determine the relationships between plasma AA concentrations and the type/degree of obesity and glucose regulation in Japanese adults with normal glucose tolerance %K Visceral obesity %K Oral glucose tolerance test %K Insulin secretion %K Insulin resistance %K Branched-chain amino acid %K Glycine %K Glutamate %K Glutamine %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717594/