%0 Journal Article
%T Associations among the plasma amino acid profile, obesity, and glucose metabolism in Japanese adults with normal glucose tolerance
%A Asuka Yamada
%A Chisa Takashina
%A Daisuke Ikeda
%A Hiroshi Ohira
%A Ichizo Tsujino
%A Masaharu Nishimura
%A Noriko Oyama-Manabe
%A Shinji Sakaue
%A Takahiro Sato
%A Taku Watanabe
%A Yoichi M. Ito
%A Yoshinori Otsuka
%J Archive of "Nutrition & Metabolism".
%D 2016
%R 10.1186/s12986-015-0059-5
%X Amino acids (AAs) are emerging as a new class of effective molecules in the etiology of obesity and diabetes mellitus. However, most investigations have focused on subjects with obesity and/or impaired glucose regulation; the possible involvement of AAs in the initial phase of glucose dysregulation remains poorly understood. Furthermore, little attention has been given to possible associations between the pattern/degree of fat deposition and the plasma AA profile. Our objective was therefore to determine the relationships between plasma AA concentrations and the type/degree of obesity and glucose regulation in Japanese adults with normal glucose tolerance
%K Visceral obesity
%K Oral glucose tolerance test
%K Insulin secretion
%K Insulin resistance
%K Branched-chain amino acid
%K Glycine
%K Glutamate
%K Glutamine
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717594/