%0 Journal Article %T Macrolide resistance in pneumococci¡ªis it relevant? %A Adam W. J. Jenney %A Allen C. Cheng %J Archive of "Pneumonia". %D 2016 %R 10.1186/s41479-016-0010-1 %X Macrolide antibiotics are widely used for a range of indications, including pneumonia. Both high-level and low-level resistance to macrolides is increasing in pneumococci globally. Macrolide resistance in pneumococci is of limited clinical relevance where £¿-lactams remain the mainstay of treatment, such as for moderate/severe pneumonia; however, data suggest that macrolides may not be able to be relied on as monotherapy for serious pneumococcal infections %K Streptococcus pneumoniae %K Antibiotic resistance %K Macrolides %K Community-acquired pneumonia %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471688/