%0 Journal Article
%T Disruption of evasive immune cell microenvironment in tumors reflects immunity induced by radiation therapy
%A Alexander Filatenkov
%A Jeanette Baker
%A Samuel Strober
%J Archive of "Oncoimmunology".
%D 2016
%R 10.1080/2162402X.2015.1072673
%X Radiation administered to murine colon tumors induced durable remissions that were dependent on CD4+ and CD8+ T cell immunity, and antigen cross priming CD8+ dendritic cells (DCs). Remissions were associated with marked reductions in the infiltration of myeloid-derived suppressor cells (MDSCs), tumor-associated macrophages (TAMs) and Treg cells, and a marked increase in CD8+ T cells
%K CD8 T cells
%K colon tumors
%K radiation therapy
%K tumor immunity
%K tumor microenvironment
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801442/