%0 Journal Article %T Cardiogenic Shock and Respiratory Failure in a Patient With Metastatic Melanoma Receiving Trametinib Therapy %J Archive of "The Oncologist". %D 2016 %R 10.1634/theoncologist.2016-0080 %X Life-threatening heart failure can occur with trametinib therapy and is reversible. This article provides recommendations for evaluation of patients receiving trametinib, including those who develop severe cardiomyopathy %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016073/