%0 Journal Article
%T Role of Magnetic Resonance Imaging in Diagnosis of Motor Neuron Disease: Literature Review and Two Case Illustrations
%A Eduardo Gonzalez-Toledo
%A Khalid Sawalha
%A Omar Hussein
%J Archive of "The Permanente Journal".
%D 2019
%R 10.7812/TPP/18-131
%X Motor neuron diseases (MNDs) are a group of devastating neurologic disorders that cause specific damage to the motor neuron cells. The current diagnosis of MND is based on results of the clinical examination and neurophysiologic studies. The length of time of referral to a neuromuscular neurologist and the lack of validated diagnostic criteria can delay diagnosis. Although the role of imaging is currently most useful in excluding other conditions, several attempts to incorporate neuroimaging in the diagnosis of the disease and assessment of progression have shown promising results
%K corticospinal tract hyperintensities
%K CST hyperintensities
%K MND
%K motor neuron disease
%K possible MND
%K possible motor neuron disease
%K quantitative and functional MRI
%K ribbon like hypointensities
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380476/