%0 Journal Article %T Chronic unpredictable mild stress induced depression-like behaviours and glutamate-glutamine cycling dysfunctions in both blood and brain of mice %A Chuang Wang %A Jiang-Ping Xu %A Ya-Ping Chen %J Archive of "Pharmaceutical Biology". %D 2019 %R 10.1080/13880209.2019.1598445 %X Context: Currently, there is no cure or early preclinical diagnostic assay available for depression. Recently, depression has been observed in association with metabolic abnormalities of the glutamate (Glu)¨Cglutamine (Gln) cycling, which is regulated by Glu, Gln and ¦Ă-aminobutyric acid (GABA) amino acids %K CUMS %K Glu %K Gln %K GABA %K HPLC %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484485/