%0 Journal Article
%T Thienopyrimidine-type compounds protect Arabidopsis plants against the hemibiotrophic fungal pathogen Colletotrichum higginsianum and bacterial pathogen Pseudomonas syringae pv. maculicola
%A Mari Narusaka
%A Yoshihiro Narusaka
%J Archive of "Plant Signaling & Behavior".
%D 2017
%R 10.1080/15592324.2017.1293222
%X Plant activators activate systemic acquired resistance-like defense responses or induced systemic resistance, and thus protect plants from pathogens. We screened a chemical library composed of structurally diverse small molecules. We isolated six plant immune-inducing thienopyrimidine-type compounds and their analogous compounds. It was observed that the core structure of thienopyrimidine plays a role in induced resistance in plants. Furthermore, we highlight the protective effect of thienopyrimidine-type compounds against both hemibiotrophic fungal pathogen, Colletotrichum higginsianum, and bacterial pathogen, Pseudomonas syringae pv. maculicola, in Arabidopsis thaliana. We suggest that thienopyrimidine-type compounds could be potential lead compounds as novel plant activators, and can be useful and effective agrochemicals against various plant diseases
%K Arabidopsis
%K Colletotrichum higginsianum
%K plant activator
%K PR-1 gene
%K Pseudomonas syringae
%K salicylic acid
%K thienopyrimidine
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399894/