%0 Journal Article %T Characterization of Schistosoma japonicum tetraspanning orphan receptor and its role in binding to complement C2 and immunoprotection against murine schistosomiasis %A Jiaojiao Lin %A Jinli Zai %A Ke Lu %A Min Zhang %A Qian Han %A Shuai Ma %A Xiaodan Cao %A Yang Hong %A Yanhui Han %A Zhiqiang Fu %A Zhixin Zhao %J Archive of "Parasites & Vectors". %D 2017 %R 10.1186/s13071-017-2229-y %X Schistosomiasis remains an important global public health problem, as millions of people are at risk of acquiring infection. An ideal method for sustainable control of schistosomiasis would be to develop an efficient vaccine. Schistosomes can survive in the host vascular system by immune evasion, regulating the host complement cascade. Schistosoma japonicum tetraspanning orphan receptor (SjTOR) is a complement regulator, which is a tegument membrane protein. To date there is no experimental evidence to explain the function of SjTOR %K Schistosoma japonicum %K Tetraspanning orphan receptor %K C2-binding receptor %K Vaccine %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466742/