%0 Journal Article
%T Congenital toxoplasmosis in the United States: clinical and serologic findings in infants born to mothers treated during pregnancy
%A Cindy Press
%A Jeanne Talucod
%A Jos¨¦ Gilberto Montoya
%A Kjerstie Olson
%A Tudor Rares Olariu
%J Archive of "Parasite".
%D 2019
%R 10.1051/parasite/2019013
%X We assessed clinical and serologic findings in 25 infants with congenital toxoplasmosis born to mothers treated during pregnancy in the United States. Results indicate a lower prevalence of eye findings and hydrocephalus in the group of infants born to treated mothers (62.5% and 38.5%, respectively) compared to results on the same pathologies reported in our previous cohort of infants born to untreated mothers (92.2% and 67.7%, respectively). The sensitivity of the IgM ISAGA and IgA ELISA in the present study were lower (44% and 60%, respectively) compared to sensitivity of these methods in our previously studied group of infants born to untreated mothers (86.6% and 76.5%, respectively). These findings provide further evidence that anti-parasitic treatment if administered during pregnancy can contribute to better clinical outcomes, even in countries where systematic screening and treatment have not been routinely implemented
%K Congenital toxoplasmosis
%K Infants
%K Laboratory diagnosis
%K Serologic findings
%K Clinical findings
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402364/