%0 Journal Article
%T Biomolecular Interaction Study of Cyclolinopeptide A with Human Serum Albumin
%A Ben Rempel
%A Bo Gui
%A Jason Maley
%A Martin Reaney
%A Ramaswami Sammynaiken
%J Journal of Biomedicine and Biotechnology
%D 2010
%I Hindawi Publishing Corporation
%R 10.1155/2010/737289
%X The kinetics, energetics, and structure of Cyclolinopeptide A binding with Human Serum Albumin were investigated with surface plasmon resonance and circular dichroism. The complex is formed through slow recognition kinetics that is temperature sensitive in the range of 20°C–37°C. The overall reaction was observed to be endothermic (¦¤=204 kJ mol£¿1) and entropy driven (¦¤=746 J mol£¿1K£¿1) with overall small changes to the tertiary structure.
%U http://www.hindawi.com/journals/biomed/2010/737289/