%0 Journal Article %T A low-carbohydrate high-fat diet decreases lean mass and impairs cardiac function in pair-fed female C57BL/6J mice %A Anna Sj£¿din %A Fredrick Anderson %A Jessica Nilsson %A Jonas Bur¨¦n %A Leif Carlsson %A Madelene Ericsson %A Masoumeh Motamedi Joibari %A Stefan K. Nilsson %J Archive of "Nutrition & Metabolism". %D 2016 %R 10.1186/s12986-016-0132-8 %X Excess body fat is a major health issue and a risk factor for the development of numerous chronic diseases. Low-carbohydrate diets like the Atkins Diet are popular for rapid weight loss, but the long-term consequences remain the subject of debate. The Scandinavian low-carbohydrate high-fat (LCHF) diet, which has been popular in Scandinavian countries for about a decade, has very low carbohydrate content (~5 E %) but is rich in fat and includes a high proportion of saturated fatty acids. Here we investigated the metabolic and physiological consequences of a diet with a macronutrient composition similar to the Scandinavian LCHF diet and its effects on the organs, tissues, and metabolism of weight stable mice %K Low-carbohydrate diet %K Heart %K Mouse %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111238/