%0 Journal Article
%T The effect of cholesteryl ester transfer protein on pancreatic beta cell dysfunction in mice
%A Beibei Gao
%A Hongwen Zhou
%A Jinxiang Fu
%A Tao Yang
%A Wen Guo
%A Wen Wang
%A Xianxia Ju
%A Xiaohui Zhu
%A Xiaoyun Liu
%A Yan Sun
%A Yina Chang
%A Yingyun Gong
%A Zhenzhen Fu
%J Archive of "Nutrition & Metabolism".
%D 2016
%R 10.1186/s12986-016-0082-1
%X Cholesterol accumulation causes pancreatic beta cell lipotoxicity and dysfunction. Cholesteryl ester transfer protein (CETP) plays an important role in blood lipid homeostasis. However, its role in tissue lipid metabolism remains unclear. We hypothesized that plasma CETP impact cholesterol homeostasis in the beta cells, thus damaging their functions
%K Cholesterol ester transfer protein
%K Free cholesterol
%K Beta cell function
%K Glucose metabolism
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788865/