%0 Journal Article %T Patterning the Axes: A Lesson from the Root %A Raffaele Dello Ioio %A Riccardo Di Mambro %A Sabrina Sabatini %J Archive of "Plants". %D 2019 %R 10.3390/plants8010008 %X How the body plan is established and maintained in multicellular organisms is a central question in developmental biology. Thanks to its simple and symmetric structure, the root represents a powerful tool to study the molecular mechanisms underlying the establishment and maintenance of developmental axes. Plant roots show two main axes along which cells pass through different developmental stages and acquire different fates: the root proximodistal axis spans longitudinally from the hypocotyl junction (proximal) to the root tip (distal), whereas the radial axis spans transversely from the vasculature tissue (centre) to the epidermis (outer). Both axes are generated by stereotypical divisions occurring during embryogenesis and are maintained post-embryonically. Here, we review the latest scientific advances on how the correct formation of root proximodistal and radial axes is achieved %K Arabidopsis %K root %K stem cells %K root development %K differentiation %K ground tissue %K radial patterning %K proximodistal patterning %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358898/