%0 Journal Article
%T Outcomes of Extracorporeal Membrane Oxygenation in Blood Culture Positive Septic Patients
%A Cameron Blazoski
%A Qiong Yang
%A Hitoshi Hirose
%J World Journal of Cardiovascular Surgery
%P 158-166
%@ 2164-3210
%D 2020
%I Scientific Research Publishing
%R 10.4236/wjcs.2020.108019
%X <b><span style=\"font-family:Verdana;\">INTRODUCTION</span></b><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">: Extracorporeal membrane oxygenation (ECMO) is commonly used for
refractory cardiac or respiratory failure. There are reported cases of
successful use of ECMO in patients with septic shock; however, there is a lack
of evidence to prove its overall efficacy. Thus, we conducted this study to
analyze the relationship between sepsis and ECMO in our own patients.</span></span></span><span><span><span style=\"font-family:;\" \"=\"\"> </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><b><span style=\"font-family:Verdana;\">METHODS</span></b></span></span><span><span><span style=\"font-family:;\" \"=\"\"><span style=\"font-family:Verdana;\">: 305 patients who were placed on ECMO between 2010 and 2020 were identified
within an IRB-approved database. Their clinical outcomes were an</span><span><span style=\"font-family:Verdana;\">alyzed with a specific focus on patients who were
septic before or during ECMO, defined as a positive blood culture. Group S was
composed of patients with a positive blood culture before or during ECMO, while
Group N was composed of all patients without a positive blood culture before or
during ECMO. The primary outcome compared between groups was </span><span style=\"font-family:Verdana;\">ECMO</span><span style=\"font-family:Verdana;\"> survival rate. </span><b><span style=\"font-family:Verdana;\">RESULTS</span></b><span style=\"font-family:Verdana;\">: Among the
305 patients on ECMO, 58 (19%) were in Group S and 247 (81%) were in Group N.
ECMO survival rates were 45% in Group S and 62% in Group N (p = 0.017).</span></span></span></span></span><span><span><span style=\"font-family:;\" \"=\"\"> </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><b><span style=\"font-family:Verdana;\">CONCLUSION</span></b></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">: Of our 305 patients, patients who were septic upon
ECMO </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">placement or those who
developed sepsis during ECMO had worse ECMO survival rates than non-septic
patients. Ultimately, patients who are septic or have a high probability of
becoming septic may not be indicated for ECMO placement, and cautious
administration of ECMO to
%K Extracorporeal Membrane Oxygenation
%K Shock
%K Sepsis
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=102625