%0 Journal Article
%T Demethoxycurcumin, a Natural Derivative of Curcumin Abrogates Rotenone-induced Dopamine Depletion and Motor Deficits by Its Antioxidative and Anti-inflammatory Properties in Parkinsonian Rats
%A Arokiasamy Justin Thenmozhi
%A Giles J. Guillemin
%A Musthafa Mohamed Essa
%A Muthu Ramkumar
%A Ranganathan Chidambaram
%A Saravana Babu Chidambaram
%A Srinivasagam Rajasankar
%A Thamilarasan Manivasagam
%A Udaiyappan Janakiraman
%A Veerapan Venkatesh Gobi
%J Archive of "Pharmacognosy Magazine".
%D 2018
%R 10.4103/pm.pm_113_17
%X Parkinson's disease (PD) is a progressive neurodegenerative disorder (NDD) associated with the loss of dopaminergic neurons in the substantia nigra and subsequently has an effect on motor function and coordination. The pathology of PD is multifactorial, in which neuroinflammation and oxidative damage are the two of the main protagonists
%K Demethoxycurcumin
%K dopamine
%K neurodegenerative disease
%K neuroinflammation
%K oxidative stress
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858249/