%0 Journal Article
%T Differences in oxidative metabolism modulation induced by ischemia/reperfusion between trained and untrained individuals assessed by NIRS
%A Juan M. Murias
%A Kaitlin M. McLay
%A Mitchell A. George
%A Rog¨¦rio N. Soares
%J Archive of "Physiological Reports".
%D 2017
%R 10.14814/phy2.13384
%X Endurance training is associated with skeletal muscle adaptations that regulate the oxidative metabolism during ischemia/reperfusion. The aim of this study was to noninvasively assess in vivo differences in the oxidative metabolism activity during ischemia/reperfusion between trained and untrained individuals, using near infrared spectroscopy (NIRS) combined with a vascular occlusion test (VOT) technique (NIRS©\VOT). Sixteen untrained (26.3 ˇŔ 5.1 year) and seventeen trained (29.4 ˇŔ 4.9 year) healthy young adult men were submitted to a VOT (2 min baseline, 5 min occlusion, and 8 min reperfusion). Oxygen utilization was estimated from the area under the curve of the NIRS©\derived deoxyhemoglobin [HHb] signal during occlusion (AUCocc). Muscle reperfusion was derived from the area above the curve (AACrep) of the [HHb] signal after cuff release. The AUCocc of the untrained participants (21010 ˇŔ 9553 % ˇ¤ s) was significantly larger than the AUCocc of their trained counterparts (12320 ˇŔ 3283 % ˇ¤ s); P = 0.001). The AACrep of the untrained participants (5928 ˇŔ 3769 % ˇ¤ s) was significantly larger than the AACrep of the trained participants (3745 ˇŔ 1900 % ˇ¤ s; P = 0.042). There was a significant correlation between AUCocc and AACrep (r = 0.840; P = 0.001). NIRS assessment of oxidative metabolism showed that trained individuals are more efficient in shifting between oxidative and anaerobic metabolism in response to ischemia and reperfusion
%K Oxygen consumption
%K Blood flow occlusion
%K Fitness
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641926/