%0 Journal Article
%T Respiratory frequency and tidal volume during exercise: differential control and unbalanced interdependence
%A Andrea Nicol辰
%A Francesco Felici
%A Ilenia Bazzucchi
%A Massimo Sacchetti
%A Michele Girardi
%J Archive of "Physiological Reports".
%D 2018
%R 10.14814/phy2.13908
%X Differentiating between respiratory frequency (fR) and tidal volume (V T) may improve our understanding of exercise hyperpnoea because fR and V T seem to be regulated by different inputs. We designed a series of exercise manipulations to improve our understanding of how fR and V T are regulated during exercise. Twelve cyclists performed an incremental test and three randomized experimental sessions in separate visits. In two of the three experimental visits, participants performed a moderate坼intensity sinusoidal test followed, after recovery, by a moderate坼to坼severe坼intensity sinusoidal test. These two visits differed in the period of the sinusoid (2 min vs. 8 min). In the third experimental visit, participants performed a trapezoidal test where the workload was self坼paced in order to match a predefined trapezoidal template of rating of perceived exertion (RPE). The results collectively reveal that fR changes more with RPE than with workload, gas exchange, V T or the amount of muscle activation. However, fR dissociates from RPE during moderate exercise. Both V T and minute ventilation ( V步E ) showed a similar time course and a large correlation with V步CO2 in all the tests. Nevertheless, V步CO2 was associated more with V步E than with V T because V T seems to adjust continuously on the basis of fR levels to match V步E with V步CO2 . The present findings provide novel insight into the differential control of fR and V T 每 and their unbalanced interdependence 每 during exercise. The emerging conceptual framework is expected to guide future research on the mechanisms underlying the long坼debated issue of exercise hyperpnoea
%K Breathing control
%K exercise hyperpnoea
%K perceived exertion
%K sinusoidal exercise
%K ventilatory pattern
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215760/