%0 Journal Article
%T Aberrantly hydroxymethylated differentially expressed genes and the associated protein pathways in osteoarthritis
%A Bing Shen
%A Jinhang Zhu
%A Juan Du
%A Lin Xia
%A Pingping Wang
%A Qing Li
%A Suwen Bai
%A Yang Fang
%A Yang Wang
%A Yonggang Shen
%J Archive of "PeerJ".
%D 2019
%R 10.7717/peerj.6425
%X The elderly population is at risk of osteoarthritis (OA), a common, multifactorial, degenerative joint disease. Environmental, genetic, and epigenetic (such as DNA hydroxymethylation) factors may be involved in the etiology, development, and pathogenesis of OA. Here, comprehensive bioinformatic analyses were used to identify aberrantly hydroxymethylated differentially expressed genes and pathways in osteoarthritis to determine the underlying molecular mechanisms of osteoarthritis and susceptibility-related genes for osteoarthritis inheritance
%K DNA hydroxymethylation
%K Expression profile
%K Bioinformatics
%K Cartilage
%K Collagen
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394344/